350,000 mutations per day

Various influences cause constant mutations in the body's cells, i.e., changes in the genetic material that can lead to degeneration. Cancer can develop from an estimated 350,000 mutations per day. The degenerated cells are normally recognized and destroyed by the immune system. Only immunological tolerance to malignant mutated cells can cause a tumor to develop. In this case, an immunological battle with the tumor has usually already taken place, but it was unsuccessful. Memory T cells remain in the immune system, which could fight the tumor again if it becomes active again. This principle is also used in our new therapy concept.

It is clear that the immune system's control mechanisms can fail, preventing it from effectively performing its guardian function. Once tumor cells have survived in the body for a while and a tumor has developed, it influences the immune system. Through various biological "camouflage mechanisms," it inhibits the aggressiveness of the immune cells and can make itself "invisible" to them. The defense cells "get used" to the tumor and do not fight it, even though it harms the organism. This immunological phenomenon is called tolerance development. It can be broken with specific immunotherapy. However, if the body's own immune system is to take the initiative, it needs relevant information about the cancer cells and activation in order to overcome tolerance.

Active versus passive treatment methods

Today's standard cancer treatment focuses on destroying cancer cells through surgery, radiation, chemotherapy, hormone therapy, passive antibody therapy, and targeted therapies. The disadvantage of these methods is that they cannot properly distinguish between diseased and healthy cells. As a result, the treatment always damages healthy tissue as well, leading to corresponding side effects. With conventional treatment methods, the patient therefore remains passive.

Immunological cancer therapy has brought about a paradigm shift: polyspecific immunological cancer therapy aims to enable the patient's immune system to become active and fight the disease on its own. This can lead to a complete cure. However, it is not necessarily necessary to destroy every cancer cell. Rather, it is now believed that a balance can be established between the tumor and the immune system, resulting in prolonged overall survival with the best possible quality of life.

Leading scientists currently recommend an individual combination of various conventional and immunological procedures. IOZK Immunotherapy is committed to this goal.