The high costs are due to the enormous amount of personnel and technical resources required: an individual medication is produced for each individual patient in strict compliance with the legal requirements of the German Medicines Act (AMG).

Since therapy is tailored to each individual patient, costs can vary considerably. Based on our experience, we can provide the following fees as a guide:

• between €6,800 and €8,500 for the laboratory tests required prior to treatment.

• Between €23,000 and €26,000 for an IO-VAC® vaccination cycle, excluding any additional antibody therapy (at least two vaccination cycles are required for treatment)

• For a five-day treatment unit to induce immunogenic cell death (e.g., as an accompanying treatment during chemotherapy or as maintenance therapy after completing the IO-VAC® vaccination cycles), between €6,000 and €11,000, excluding any additional antibody therapy.

These amounts do not include any additional costs for individual medications (infusions). The patient agrees to cover the treatment costs, regardless of any reimbursement from insurance companies.

The costs of diagnosis and treatment may be reimbursed by private health insurance companies (depending on the contract taken out), assistance agencies, and professional associations. Immunotherapy is not included in the list of services covered by statutory health insurance. However, under certain circumstances, the costs may be covered on a case-by-case basis upon application.