Generation of Tumor-specific T Lymphocytes Using Dendritic Cell/Tumor Fusions and Anti-CD3/CD28. Feb 2010 - :1537-4513 [PMID:20145548] [Rosenblatt J] [Wu Z] [Vasir B] [Zarwan C] [Stone R] [Mills H] [Friedman T] [Konstantinopoulos PA] [Spentzos D] [Ghebremichael M] [Stevenson K] [Neuberg D] [Levine JD] [Joyce R] [Tzachanis D] [Boussiotis V] [Kufe D] [Avigan D]
Fusions of dendritic cells with breast carcinoma stimulate the expansion of regulatory T cells while concomitant exposure to IL-12, CpG oligodeoxynucleotides, and anti-CD3/CD28 promotes the expansion of activated tumor reactive cells. Jun 2008 - J. Immunol.; 181(1):0022-1767 [PMID:18566447] [Vasir B] [Wu Z] [Crawford K] [Rosenblatt J] [Zarwan C] [Bissonnette A] [Kufe D] [Avigan D]