A phase I clinical study of vaccination of melanoma patients with dendritic cells loaded with allogeneic apoptotic/necrotic melanoma cells. Analysis of toxicity and immune response to the vaccine and of IL-10 -1082 promoter genotype as predictor of disease progression.
Mar 2008 - J Transl Med; 6:1479-5876 [PMID:18221542]
[von Euw EM] [Barrio MM] [Furman D] [Levy EM] [Bianchini M] [Peguillet I] [Lantz O] [Vellice A] [Kohan A] [Chacón M] [Yee C] [Wainstok R] [Mordoh J]

Monocyte-derived dendritic cells loaded with a mixture of apoptotic/necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8(+) T lymphocytes.
May 2007 - J Transl Med; 5:1479-5876 [PMID:17448240]
[von Euw EM] [Barrio MM] [Furman D] [Bianchini M] [Levy EM] [Yee C] [Li Y] [Wainstok R] [Mordoh J]